0:00-0:42: Intro
0:43-1:53: Introduction of Dr. Kazuhiko Kido
1:54-6:02: Trial Overview
6:03-9:09: Previous Data for LV Thrombus Management
9:10-10:10: Overall Thoughts
10:11-12:44: Trial Limitations
12:45-15:01: Background Medications and LV Thrombus secondary to ischemic cardiomyopathy vs. non-ischemic cardiomyopathy
15:02-19:08: LV thrombus anticoagulation management in patients
19:09-19:54: Closing
References:
- Robinson AA, Trankle CR, Eubanks G, et al. Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi. JAMA Cardiol 2020;5(6):685-692.
- Vaitkus PT, Barnathan ES. Embolic potential prevention and management of mural thrombus complicating anterior myocardial infarction: a meta-analysis. J Am Coll Cardiol 1993;22(4):1004-1009. doi:10.1016/0735-1097(93)90409-T.
- Robinson A, Ruth B, Dent J. Direct oral anticoagulants compared to warfarin for left ventricular thrombi: a single center experience. J Am Coll Cardiol 2018;71(11)(suppl):A981. doi:10.1016/S0735-1097(18)31522-5
- Cochran JM, Jai X, Hamzeh I, and Birnbaum Y. Direct oral anticoagulant use for left ventricular thrombus: a single center experience. Circulation 2018;138(suppl_1)A16411.
- McCarthy CP, Murphy S, Venkateswaran RV, et al. Left ventricular thrombus: contemporary etiologies, treatment strategies, and outcomes. J Am Coll Cardiol 2019;73(15):2007-2009. doi:10.1016/j.jacc.2019.01.031.
- Fleddermann AM, Hayes CH, Magalski A, and Main ML. Efficacy of direct acting oral anticoagulants in treatment of left ventricular thrombus. Am J Cardiol 2019;124(3):367-372. doi:10.1016/j.amjcard.2019.05.009.