Author Archives: cardioscripts

Dr. Sarah Schaidle discusses factor XI inhibitors and the OCEANIC-AF trial with CardioScripts co-host Dr. Nathan Wayne. 0:00-0:59: Introduction 0:56-4:26: OCEANIC-AF trial overview 4:27-7:08: Overview of Factor XI (FXI) inhibition 7:09-08:29: New drug targets for FXI inhibition 08:30-11:17: OCEANIC-AF trial discussion 14:01-17:03 : Other areas of interest for FXI inhibitors  17:04-19:23: Ongoing phase 3 trialsContinue reading “The OCEANIC-AF Trial”

This episode is a rebroadcast of the ACCP Cardiology PRN webinar where Drs. Vicki Groo and Ian Hollis reviewed several different presentations from the ACC and ISHLT meetings. 

This episode is a rebroadcast of the ACCP Cardiology PRN webinar where Drs. Kristen De Almeida and Augustus (Rob) Hough reviewed the DANGER-SHOCK and ULTIMATE-DAPT trials released at the ACC 24 meeting.  The views expressed in this presentation reflect those of the presenter, and not necessarily those of the Department of Veterans Affairs or PublicContinue reading “ACC/ISHLT 2024 Recap (Part 2)”

This episode is a rebroadcast  of the ACCP Cardiology PRN webinar where Drs. Tracy Macaulay and Bill Larsen reviewed the REDUCE-AMI and EMPACT-MI trials released at the ACC 24 meeting.  0:00-2:19: Introduction 2:05-9:24: The REDUCE-AMI Trial 9:25-14:19: The EMPACT-MI Trial 14:20-17:58: Questions 17:59-18:36: Closing thoughts References: REDUCE-AMI Yndigegn T, Lindahl B, Mars K, et al.Continue reading “ACC/ISHLT 2024 Recap (Part 1)”

Dr. Tomasz Jurga discusses the CLEAR Outcomes trial and current cholesterol management considerations with co-host, Dr. Liz Wang.  0:00-2:19: Introduction 2:20-7:13: TIME trial overview 7:14-11:18: What is bempedoic acid? 11:19-16:45: What is the current landscape of cholesterol management? 16:46-20:54: Previous CLEAR trials: Tranquility, Serenity, Harmony, Wisdom 20:55-28:55: CLEAR Outcomes overall thoughts 28:56-32:38: Where does bempedoicContinue reading “The CLEAR Outcomes Trial”

Dr. Ricky Turgeon discusses the TIME Trial with co-host, Dr. Liz Wang. 0:00-1:09: Introduction 1:10-7:16: TIME trial overview 7:17-9:10: When to take blood pressure medications? 9:11-14:37: Previous trials 14:38-19:08: Thoughts on the TIME trial and key takeaways 19:09-19:34: Closing References: TIME Trial Cardiovascular Outcomes in Adults With Hypertension With Evening Versus Morning Dosing of UsualContinue reading “The TIME Trial”

Dr. Steve Antoine discusses the STRONG-HF trial with co-host, Dr. Liz Wang. 0:00-2:37: Introduction 2:38-7:54: STRONG-HF trial overview 7:55-11:44: Overall thoughts 11:45-13:45: Baseline therapies 13:46-19:59: Discussion of titration and follow up in the trial 20:00-21:22: Ejection fraction considerations 21:23-23:22: Final thoughts 23:23-23:58: Closing References: STRONG-HF Mebazaa A, Davison B, Chioncel O, et al. Safety, tolerabilityContinue reading “The STRONG-HF Trial”

In this special episode the CardioScripts crew join Pharmacy to Dose podcast creator and host, Nick Peters, to discuss his Top 3 Trials in cardiology. Listen to the full episode on the Pharmacy to Dose podcast (https://pharmacytodose.com/) where you can also find a full list of references! 

Dr. Sara Ward discusses the SECURE trial with co-host, Dr. Tracy Macaulay 0:00-1:08: Introduction 1:09-3:40: SECURE trial overview 3:41-7:55: History of polypill and overall trial considerations 7:56-11:36: Polypill formulation and titration 11:37-14:04: Antiplatelet therapy in SECURE discussion 14:05-18:06: Polypill use in the US 18:07-19:29: Final thoughts 19:30-20:00: Closing References:  SECURE Castellano JM, Pocock SJ, BhattContinue reading “The SECURE TRIAL”

Dr. Noelle Leung discusses the CHAP trial with co-host, Dr. Tracy Macaulay. 0:00-0:55: Introduction 0:56-4:32: CHAP trial overview 4:33-17:40: Overall thoughts and discussion  17:41-19:55: Collaboration in patient care 19:56-23:38: Use of aspirin  23:39-24:37: Final thoughts 24:38-25:12: Closing References: CHAP Tita AT, Szychowski JM, Boggess K, et al. Treatment for Mild Chronic Hypertension during Pregnancy. N EnglContinue reading “The CHAP Trial”